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Tai biến mạch máu não

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Năm 2004, tai biến và các bệnh mạch máu não khác gây ra khoảng 5,7 triệu cái chết, chiếm 9,7% ca tử vong trên toàn thế giới. Năm 2008, con số này là 6,15 triệu, chiếm đến 10,8% các ca tử vong. Đến nay, tỷ lệ này vẫn không ngừng gia tăng.

 Tai biến mạch máu não cướp 100.000 sinh mạng mỗi năm

Mỗi năm Việt Nam có khoảng 200.000 người mắc bệnh lý tai biến mạch máu não, gần một nửa trong số đó tử vong. Gốc tự do được cho là nguyên nhân dẫn đến bệnh lý mạch máu não và thoái hóa tế bào thần kinh.

Riêng TP HCM, các thống kê cho thấy khoảng 19.000 người bị tai biến mỗi năm, trong đó chừng 1.000 trường hợp tử vong. Chưa có thống kê cụ thể nhưng nhìn chung độ tuổi bệnh nhân gặp phải các cơn tai biến mạch máu não đang ngày một trẻ hóa, thậm chí nhiều ca nhập viện chưa đến tuổi 20.

Từ năm 1990, nghiên cứu Gánh nặng Bệnh tật Toàn cầu (GBD) của Tổ chức Y tế thế giới (WHO) đã xếp các bệnh mạch máu não ở vị trí thứ hai trong danh sách bệnh gây tử vong cao nhất, chỉ sau bệnh tim mạch. Vị trí này không hề thay đổi trong suốt các báo cáo y học sau này, kể cả trong dự báo về các nguyên nhân tử vong cho đến năm 2030.

Thiếu máu não thoáng qua, đau nửa đầu là những bệnh mạch máu não thường gặp.

Năm 2004, tai biến và các bệnh mạch máu não khác gây ra khoảng 5,7 triệu cái chết, chiếm 9,7% ca tử vong trên toàn thế giới. Năm 2008, con số này là 6,15 triệu, chiếm đến 10,8% các ca tử vong. Đến nay, tỷ lệ này vẫn không ngừng gia tăng. Các bệnh mạch máu não thường gặp là thiếu máu não thoáng qua, đau nửa đầu…

Có nhiều nguyên nhân dẫn đến bệnh lý mạch máu não, trong đó vai trò của gốc tự do đang ngày càng được quan tâm. Phó giáo sư Tiến sĩ Trần Đáng, nguyên Cục trưởng An toàn vệ sinh thực phẩm cho biết: “Gốc tự do là những yếu tố có hại sinh ra từ quá trình chuyển hóa của cơ thể và từ ảnh hưởng của các tác nhân bên ngoài. Chúng được y học hiện đại xem là nguồn gốc của sự lão hóa và rất nhiều bệnh tật”.

Theo đó, gốc tự do là nguyên tử – phân tử bị mất một điện tích, có tính chất kém ổn định nên phải liên tục tìm và cướp lấy điện tích từ các nguyên tử – phân tử xung quanh. Trong quá trình này, chúng liên tục biến những “nạn nhân” của mình thành gốc tự do mới, dẫn đến biến đổi gây tổn hại, rối loạn và làm chết tế bào. Não bộ là nơi sinh ra nhiều gốc tự do nhất nên chịu ảnh hưởng nhiều hơn cả.

Với mạch máu não, chúng tấn công mạnh và gây tổn thương thành mạch, tạo điều kiện cho sự hình thành mảng xơ vữa. Các mảng này lớn dần, làm hẹp các động mạch khiến giảm lưu lượng máu lưu thông gây nên tình trạng thiếu máu cục bộ. Đó chính là tình trạng thiếu máu não thoáng qua hoặc trầm trọng hơn là tai biến mạch máu não. Những biến đổi giãn nở của mạch máu não cũng có thể làm xuất hiện các cơn đau nửa đầu, gây chóng mặt, rối loạn thị giác kèm theo buồn nôn. Cơn đau nửa đầu phức tạp có thể làm ảnh hưởng các chức năng của não.

“Ngoài ảnh hưởng đến mạch máu, gốc tự do còn làm tổn thương các tế bào thần kinh não, gây ra các bệnh về thoái hóa thần kinh như suy giảm trí nhớ, sa sút trí tuệ, alzheimer, parkinson…”, PGS Trần Đáng cho biết thêm. Theo ông, người bệnh đái tháo đường, mỡ trong máu cao, stress triền miên dễ bị hẹp lòng động mạch nhất. “Không ai được phép chủ quan, vì theo thời gian thì những tổn thương thành mạch máu do gốc tự do gây ra hầu như không thể tránh khỏi”, ông nói.

Trung bình đến tuổi 70, trong cơ thể người vừa hình thành vừa liên tục trung hòa tổng cộng khoảng 17 tấn gốc tự do. Sau tuổi 30, gốc tự do xuất hiện ngày càng nhiều trong khi khả năng trung hòa của cơ thể bắt đầu giảm sút. Điều này lý giải vì sao nguy cơ các bệnh mạch máu não, thoái hóa thần kinh tăng cao theo độ tuổi.

Theo bác sĩ, các chất chống gốc tự do trong thảo dược, rau quả… có thể giúp bảo vệ mạch máu não và tế bào thần kinh não. Tuy nhiên, chúng chỉ có thể đạt hiệu quả nếu vượt qua hàng rào máu não – một rào chắn sinh học kiểm soát tất cả các chất đưa vào não.

PGS Trần Đáng cũng khẳng định: “Bổ sung các chất chống gốc tự do từ thiên nhiên là một vũ khí tốt để chăm sóc sức khỏe cho não bộ. Tuy nhiên nên biết rằng gốc tự do sẽ sinh ra nhiều hơn nếu thiếu dinh dưỡng, stress kéo dài hay sống trong môi trường ô nhiễm”. Vì vậy, theo ông, duy trì chế độ dinh dưỡng cân đối, sinh hoạt có quy luật, vận động vừa sức, giữ cho tinh thần lạc quan, tâm lý cân bằng và tránh các tác nhân có hại như thuốc lá, hóa chất diệt cỏ – diệt côn trùng… là vô cùng cần thiết.

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    cells, which transport oxygen to the muscles and improve stamina.
    In contrast to Anavar, less analysis has been carried out on Winstrol with regard to the
    liver. Nonetheless, we do know that very modest dosages (12.5 mg/day) have little impact on ALT and AST enzymes (4).
    Whereas we see excessive dosages of Winstrol having the power to
    cause severe hepatotoxicity, even in wholesome bodybuilders (5).

    Nonetheless, this does not stop athletes from taking and reaping
    the advantages of Anavar. It is well-known for significantly increasing power, lean mass while lowering body fats in customers.

    One of the unique traits of oxandrolone is its capacity to extend muscle
    mass with out gaining water or fats. This is contrary to many
    different bulking compounds which may depart you feeling puffy
    or bloated (not perfect for an athlete). Anavar is an oral anabolic steroid
    derived from dihydrotestosterone (DHT).
    It’s advisable to start out on the decrease end of the
    dose vary, especially for first-time users, and gradually improve if needed based on results and tolerance levels.

    Exceeding beneficial doses considerably increases
    the danger of unfavorable unwanted effects. Correct food regimen, coaching,
    and cycle help are important for getting essentially the most out of an Anavar
    cycle safely and successfully. Anavar can also trigger masculinization in women; nevertheless, we do not usually observe this in therapeutic doses.

    Nonetheless, excessive dosages or combining Anavar with different anabolic steroids such as Winstrol will increase the probability of masculinization. Anavar may even trigger
    elevations in liver enzymes, marking a level of hepatic stress.

    This is due to Anavar being 5α-reduced; thus, it does not aromatize, which means estrogen ranges remain steady.
    This is beneficial for bodybuilders looking for a lean and defined physique.
    It is also interesting to athletes who are not trying for further water weight when performing.

    This ought to be sufficient of a cause to keep away from taking it as knowledgeable athlete, however I feel customers must be much more apprehensive concerning the
    quite a few side effects this drug can doubtlessly cause.
    From my time in the ring, I’ve seen how Anavar boosts muscle growth and bone growth.

    There can be one thing to be stated about combining an Anavar dosage with caffeine.
    One examine has demonstrated that simply 300mg of caffeine administered alongside Anavar elevated subjects’ blood plasma levels of Anavar by
    15 – 20x compared to baseline levels[10].
    The dosage of Anavar will also play a task in fat loss, with low dosages
    having less of an effect. As mentioned within the part about buying Anavar, this drug is illegal without
    a prescription in most locations. This consists of the United
    States, the place oxandrolone is assessed as a Schedule III drug as a
    half of the Controlled Substances Act (CSA). This implies that easy possession of Anavar tablets
    might end in up to a $250,000 nice and three years in prison.

    References:

    do strongmen Use steroids

  92. Git.Info666.Com says:

    So many components influence your outcomes when using this (or any
    other) steroid. Having a PCT plan ready to go for the top of your Anavar cycle
    is an easy method of avoiding low testosterone. And similar to the constructive outcomes,
    the standard of your Anavar can play a BIG half within the sorts and severity of
    unwanted effects. This is another reason we must always keep away
    from poor-quality Oxandrolone on the black market by only buying from dependable suppliers.
    The dosing of Clen all the time must be tapered up to keep away from outcomes plateauing as your
    body adjusts. Masteron is thought to be a better temper enhancer than Anavar, but this
    impact may be very individual-dependent. Most Masteron users may even see
    a higher enhance to the libido than is normally skilled with
    Anavar.
    BTG was granted orphan drug designation for treating uncommon muscle-wasting illnesses and conditions similar to AIDS, Turner syndrome,
    and muscular dystrophy. This gave BTG seven years of
    market exclusivity, resulting in a pharmaceutical monopoly.

    Consequently, BTG was in a place to significantly improve the
    worth of Anavar by 1,200%. The subsequent factor to recollect is to
    ditch the fake product and not utilizing a second thought.
    Holding onto it would tempt you or others who’ve access to it to attempt it out despite the dangers.

    Importantly, Winstrol is considered to have a extra powerful anabolic to androgenic impact in contrast with testosterone.
    Many customers nonetheless expertise unwanted effects similar to
    nausea, headaches, hair loss, and zits. Not only do they become much less effective
    over time, but also fixed use will increase the unwanted facet effects
    and long-term injury to the physique.
    Females looking at utilizing Winstrol normally need to use
    it for bulking, chopping, and/or contest prep. Like Anavar, females might be very aware of Winny’s anabolic effects, leading to
    substantial muscle growth (if the diet supports it).

    As with all oral steroids, the poisonous effects on the liver make
    it unsuitable and doubtlessly harmful to take for longer than eight weeks.

    On the same observe, those who can’t stand injecting themselves with it typically love liquid as a end result of it’s simpler to take with out negative side effects.
    By now, it had turn out to be famous as a bootleg performance-enhancing drug and was bringing the company
    plenty of dangerous press. Most performance-enhancing substances didn’t start out getting used for that purpose.
    Anyone who has read one of these steroid articles is
    probably fairly used to hearing that. Oxandrolone Magnus
    is designed to be a variation on Anavar that focuses closely on burning fat and growing your muscle hardness.

    In truth, this profit is among the primary causes that Anavar has turn out
    to be in style for chopping. One of an important features of Anavar is its capacity to burn fats off
    of your physique.
    Combining 5 of our strongest muscle building and fats burning formulation for wonderful,
    fast-acting outcomes. Step on the human progress hormone fuel,
    fire up muscle progress and burn by way of fat stores. Anavar can doubtlessly trigger hair loss or male pattern baldness in individuals who’re genetically predisposed to it.
    This is as a end result of conversion of testosterone to dihydrotestosterone
    (DHT) which might trigger hair follicles to shrink and ultimately cease producing hair.

    Unlike many different popular steroids used right now, Anavar
    does not aromatize or convert to estrogen in the physique.
    This implies that you must use Anavar without the worry
    of breast growth for males, a case often recognized as gynecomastia.

    It additionally boosts the making of pink blood cells, which carry oxygen to muscles, helping you last more.
    Nonetheless, it’s necessary to note that these steroids
    can enhance efficiency. Moreover, it is most likely not permitted in competitive sports
    activities as a outcome of anti-doping regulations. Females can consider beginning at
    an very low dose of two.5mg of Anavar daily for these simply beginning their
    most first cycle and who must take probably the most safe technique.
    Most girls, regardless their particular objectives
    or purpose in using Anavar, can comfortably start at 5mg or even 10mg per day and have confidence that
    the chance of unwanted facet effects is low.
    Since Anavar is a DHT primarily based compound, customers might experience
    thinning of the hair on the scalp. However, there could probably be a
    rise within the progress of hair all over the place else. For individuals
    with MPB (male sample baldness) of their household, they might be vulnerable to losing their hair.
    For those who are luckier, they might simply hold on to their beloved hair follicles.
    If you’re buying anavar for its capacity to burn fats and you’re brief
    on money, a extra cost-efficient selection may be
    clenbuterol. You’re additionally much less
    likely to get scammed shopping for clen as it’s a more common drug in comparison with oxandrolone.
    If you’re situated in the UK, US or other international locations the place
    anavar’s unlawful – you need to very cautious.

    This makes their results milder in comparison to steroids, however without practically as
    many unwanted effects. Anavar is known for its strength-building properties, making it a popular selection amongst
    these teams. While LGD 4033 also can increase
    energy, it may not be as potent as Anavar. The best option will in the end
    come down to private choice and individual response.
    Ultimately, the selection is up to you and what you prioritize more – short-term gains or long-term health.

    Full muscles may help you seem greater than you are out and in of the gym
    while additionally encouraging additional progress due to stretching of the
    muscle fascia. This impact creates an outlined and full look on Anavar, whereas on Winstrol,
    a toned appearance is widespread, however with less of a pump to the muscular tissues.

    In terms of administration, Anavar comes as an oral pill like Winstrol.
    Purchasing Anavar on-line offers convenience, nevertheless
    it requires vigilance to make sure the product’s security
    and legality. Taking the best precautions can help you avoid
    counterfeit items and unreliable suppliers, ensuring a secure transaction and effective
    outcomes. For those in search of Anavar in the USA, compliance with federal and state rules is paramount.

    References:

    Steroids Bodybuilding Side Effects (Git.Info666.Com)

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